• br Conclusions and recommendations The

  2020-08-08

  

  Conclusions and recommendations The compressive strength of RHA replacement in cement concrete is in the order of alkali attack>water curing>acid attack. For the case of without RHA, the compressive strength water curing>alkali attack>acid attack was observed. Hence, RHA replacement in cement con

• br Materials and methods br Results br Discussion

  2020-08-08

  

  Materials and methods Results Discussion Apoptosis plays a major role in the development of neurons, and a defect in the apoptosis process may underly various neurodevelopmental disorders (Xia et al., 1995; Mattson, 2000). Hippocampal neuron apoptosis also plays a significant role in the de

• The survivin protein has also been

  2020-08-08

  

  The survivin protein has also been implicated in cell growth in many cancers. Pathological evidence has shown a significant correlation between survivin expression and tumor stage, prognosis, and recurrence (Barnes et al., 2006, Atikcan et al., 2006, Ye et al., 2007, Lee et al., 2005). Downregulatio

• DNA methylation is associated with transcriptional silencing

  2020-08-07

  

  DNA methylation is associated with transcriptional silencing of tumor suppressors or other genes important for normal cellular function and plays an important role in the development of cancer and other diseases (such as breast and colorectal cancers) [19]. DNA methyltransferases (MTases) are a fami

• br Biological functions of ENO br Conclusions br Acknowledge

  2020-08-06

  

  Biological functions of ENO1 Conclusions Acknowledgement The work was supported by the Natural Science Foundation of China (31302052) and the Natural Science Foundation of Heilongjiang Province of China (ZD201116). The authors would like to thank the anonymous reviewers for their valuable c

• br Materials and methods br Results br Discussion Kaempferia

  2020-08-06

  

  Materials and methods Results Discussion Kaempferia parviflora has been long used as a herbal medicine. Methoxyflavones, which are the major components in this plant, can be used as standards for the characterization of Kaempferia parviflora extract. They can be identified and quantified by

• As a newly emerging technology nanoparticles or nanoclusters

  2020-08-06

  

  As a newly emerging technology, nanoparticles or nanoclusters templated by DNA have attracted research interest as these baf312 have the advantages of simplifying synthesis, utilizing flexible mechanisms and powerful signals, and having low cost, as well as the ability to be templated by proteins o

• Lsodren br Introduction The stroma associated with breast ca

  2020-08-06

  

  Introduction The stroma associated with breast cancer metastasis consists of extracellular matrix (ECM) proteins, including fibrillar collagens, and a cellular component comprised of mesenchymal stem/multipotent stromal Lsodren (MSCs), vessels, and cells of the immune system (Pein and Oskarsson,

• The current study revealed that C

  2020-08-06

  

  The current study revealed that C. albicans infection elevated serum ALT and AST activities as well as butyrylcholinesterase as compared to the control value. Increased liver kynurenine were pointed to cellular leakage indicating liver damage. It has been previously demonstrated that numerous liver

• We did not find any significant associations

  2020-08-06

  

  We did not find any significant associations between APOE genotype and BDI-II, BAI, or PAI clinical scale scores. Our results indicate that APOE is not likely to play a major role in psychiatric comorbidities in epilepsy. This is in line with studies in the general population, which have not found a

• The discoidin domain receptors DDR and DDR are receptor

  2020-08-05

  

  The discoidin domain receptors, DDR1 and DDR2, are receptor tyrosine kinases that are activated by different types of collagen (Shrivastava et al., 1997, Vogel et al., 1997). Both receptors interact with a number of fibrillar collagens, and DDR1, but not DDR2, is also activated by the network-formin

• Another objective of the current study

  2020-08-05

  

  Another objective of the current study was to examine possible correlations between clinical and laboratorial features of MGUS, SMM, and MM and the methylation pattern of the 4 evaluated genes at diagnosis. We found that patients with p16 gene methylation were more likely to have advanced ISS stage

• This study also found that CuE significantly inhibited P gp

  2020-08-05

  

  This study also found that CuE significantly inhibited P-gp activity with no effect on its expression. Since CuE presented potent inhibition on both CYP3A and P-gp activities in vitro, it may increase the exposed quantity of co-administered drugs in the body and cause drug-induced toxicity. To clari

• The HPA axis controls its

  2020-08-05

  

  The HPA axis controls its own activity through a negative feedback mechanism exercised by glucocorticoids (Keller-Wood, 2015), which limits the hypothalamic corticotropin-releasing factor (CRF) secretion and the pituitary SCH-900776 release (Keller-Wood, 2015). CRF binds to its specific receptors (

• Hypermethylation of CpG islands in

  2020-08-05

  

  Hypermethylation of CpG islands in cancer exhibits heterogeneity both within the same tumor types and among different tumor types.36, 37 Methylated CpG islands are often, but not always, associated with transcriptional silencing.38, 39 A recent study suggested that aberrant methylation of CpG island

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